Programme at the Glance

Programme at the Glance –
Thursday 14 October 2021

08.45
09.40

Belgian Society for Thrombosis and Haemostasis

Chair: Jan Emmerechts and Phu Quoc Lee
08.45 – 08.50 Introduction by the President of the BSTH
08.50 – 09.15 Thrombotic antiphospholipid syndrome – Katrien Devreese, Ghent
09.15 – 09.40 Inherited antithrombin deficiency revisited: novel insights in laboratory diagnosis and clinical presentation – Christelle Orlando, Brussel

09.40
09.55

Short Break

09.55
10.45

Belgian Society for Thrombosis and Haemostasis

Chair: Simon Demeyer and Thomas Vanassche
09.55 – 10.20 Importance of the novo lipogenesis in platelet production and function – Sandrine Horman, Louvain-la-Neuve
10.20 – 10.45 Ticagrelor: a potent antiplatelet drug with unprecedented anti-staphylococcal activity – Cécile Oury , Luik

10.45
11.00

Short Break

11.00
11.45

Belgian Society for Thrombosis and Haemostasis

Chair: Philip Maes and Kristin Jochmans
11.00 – 11.15 Presentation by the winner of the Clinical/Laboratory prize – First report of a de novo iTTP episode associated with an mRNA-based anti-COVID-19 vaccination, Severine De Bruijn, Antwerp
11.15 – 11.30 Presentation by the winner of the Basic science prize – Neutrophils promote the progression of Staphylococcus aureus endocarditis, Severien Meyers, Leuven

Chair: Alain Gadisseur and Kristel Vandenbosch
11.30 – 11.45 Presentation by the winner CSL Behring encouragement award

11.45
12.00

Short Break

12.00
12.30

Special Symposium

12.30
12.40

Short Break

12.40
12.45

Opening

12.45
13.30

Keynote Lecture

13.30
13.45

Short Break

13.45
14.45

Oral Communications

OS 1.1 – 13.45 – 13.57: Selective serotonin reuptake inhibitor use is associated with major bleeding during treatment with vitamin K antagonists: results of a cohort study, Louise Burggraaf, The Netherlands

OS 1.2 – 13.57 – 14.09: Critical role of fibrin gamma-chain crosslinking by FXIIIa in preventing thrombus fragmentation and subsequent embolisation, Cédric Duval, United Kingdom

OS 1.3 – 14.09 – 14.21: Platelet-specific acetyl-CoA carboxylase 1 deletion decreases phospholipid content and impairs platelet functions, Marie Octave, Belgium

OS 1.4 – 14.21 – 14.33: TLR3 promotes venous thrombosis through endothelial cell activation, Maria Najem, France

OS 1.5 – 14.33 – 14.45: Exploring new candidate mechanisms behind antithrombin deficiency in cases with unknown molecular basis: mosaicism and intronic profiles, Pedro Garrido-Rodríguez, Spain

14.45
15.30

Keynote Lecture

15.30
15.45

Short Break

15.45
16.45

Oral Communications

OS 2.1 – 15.45 – 15.57: A hemostatic chemical compound against bleedings induced by direct oral anticoagulants., Maximilien Desvages, France

OS 2.2 – 15.57 – 16.09: Presence and evolution of NET markers and DAMPS in critically ill COVID-19 patients, Joram Huckriede, The Netherlands

OS 2.3 – 16.09 – 16.21: Maintaining flippase activity in procoagulant platelets is a novel approach to reducing thrombin generation., Sarah Millington-Burgess, United Kingdom

OS 2.4 – 16.21 – 16.33: Hypoxia augments proinflammatory activation of endothelial cells towards a prothrombotic phenotype, Casper Ullsten-Wahlund, Norway

OS 2.5 – 16.33 – 16.45: Derivation of a predictive score for venous thromboembolism in women using combined oral contraceptives, Pierre Suchon, France

16.45
17.45

Science, Fast and Furious

SF1.1 – 16.45 – 17.00: Correlation of calibrated automated thrombogram parameters with clinical phenotype in a large cohort of patients with antithrombin deficiency carrying different SERPINC1 variants, Carlos Bravo-Perez, Spain

SF1.2 – 17.00 – 17.15: Inhibition of ADAMTS13 Rescues Acquired von Willebrand Syndrome in a Preclinical Left Ventricular Assist Device Animal Model, Shannen J. Deconinck, Belgium

SF1.3 – 17.15 – 17.30: S100A8/A9 levels are increased in COVID-19 patients and induce procoagulant platelets in a GPIbα-dependent manner, Martina Colicchia, United Kingdom

SF1.4 17.00 – 17.45: Protease Nexin-1, a serpine participating in neutrophil recruitment through CD11a integrin regulation, Célina Madjene, France

17.45
18.00

Short Break

18.00
20.00

Poster Awards and Drinks

08.30
09.30

Oral Communications

OS 3.1 – 08.30 – 08.42: Genetic and clinical determinants of the outcome of immune tolerance induction in severe hemophilia A – preliminary results, Ilja Oomen, The Netherlands

OS 3.2 – 08.42 – 08.54: The Extracellular Protease EpiP from S. aureus Triggers Blood Coagulation by Proteolytically Activating Prothrombin and Platelet Protease-Activated Receptor 1, Vincenzo De Filippis, Italy

OS 3.3 – 08.54 – 09.06: Activation mechanism dependent surface exposure of cellular FXIII on platelets and platelet microparticles: immunofluorescence and immune electron microscopic study, László Muszbek, Hungary

OS 3.4 – 09.06 – 09.18: Protein S Gla domain as theranostic for early vascular calcification, Anouk Gentier, Belgium

OS 3.5 – 09.18 – 09.30: Remote history of venous thrombosis and the risk of venous thrombosis beyond the age of 70 years, Huijie Wang, The Netherlands

09.30
10.15

Keynote Lecture

10.15
10.30

Short Break

10.30
11.30

Oral Communications

OS 4.1 – 10.30 – 10.42: COVID-19 associated coagulopathy in acute ischemic stroke patients treated with intravenous thrombolysis, Zsuzsa Bagoly, Hungary

OS 4.2 – 10.42 – 10.54: Joint effect of multiple prothrombotic genotypes and mean platelet volume on the risk of incident venous thromboembolism, Lisa Jakobsen, Norway

OS 4.3 – 10.54 – 11.06: Shear-induced platelet GPIbα shedding under extracorporeal membrane oxygenation promotes platelet clearance independently from von Willebrand factor-GPIbα interaction, Annabelle Dupont, France

OS 4.4 – 11.06 – 11.18: Effects of dietary palmitate on blood lipid profile and calcification of aorta and aortic valve, Nathalie Donis, Belgium

OS 4.5 – 11.18 – 11.30: Lower excess mortality in an anticoagulated population during the first wave of the COVID-19 pandemic in the Netherlands, Qingui Chen, The Netherlands

11.30
12.00

How to and Meet the expert

12.00
12.15

Short Break

12.15
13.15

Special Symposium

13.15
13.30

Short Break

13.30
14.30

Oral Communications

OS 5.1 – 13.30 – 13.42: A novel quali-quantitative defect of VWF, Tom van de Berg, The Netherlands

OS 5.2 – 13.42 – 13.54: Anti-cysteine/spacer autoantibodies that open the conformation of ADAMTS13 are a common feature of the autoimmune response in immune-mediated thrombotic thrombocytopenic purpura, Laure De Waele, Belgium

OS 5.3 – 13.54 – 14.06: GPVI is a binding partner for pro-coagulant factor VIII on platelets, Rohini Sekar, France

OS 5.4 – 14.06 – 14.18: Highly reactive juvenile platelets express higher levels of GPVI in a size-related manner, Alicia Veninga, The Netherlands

OS 5.5 – 14.18 – 14.30: SARS-CoV2 associated venous thromboembolism – a one-year follow-up, Alberto Maino, Italy

14.30
14.45

Short Break

14.45
15.57

Oral Communications

OS 6.1 – 14.45 – 14.57: Prosthetic valve bioactive surface coating to reduce the prevalence of thrombosis, Cecile Oury, Belgium

OS 6.2 – 14.57 – 15.09: Venous Thromboembolism after Incident Colorectal Cancer in the Netherlands: Incidence, Predictors, and Prognosis, Rayna Anijs, The Netherlands

OS 6.3 – 15.09 – 15.21: Identification of two new ligands of the platelet CLEC-2 receptor, Luis A. Moran, United Kingdom

OS 6.4 – 15.21 – 15.33: Elevated plasma levels of the complement activating enzyme MASP-2 are associated with risk of future incident venous thromboembolism, Christabel Esi Damoah, Norway

OS 6.5 – 15.33 – 15.45: Role of Matrix Gla Protein in vascular calcification: hard chemistry for soft vessels, Stijn Agten, The Netherlands

OS 6.6 – 15.45 – 15.57: Global seroprevalence of pre-existing immunity against AAV serotypes in people with hemophilia A, Brigitte Pan-Petesch, France

15.57
16.15

Short Break

16.15
17.00

Keynote Lecture

17.00
17.15

ECTH Closing

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