Elisabetta Castoldi studied Biology (with a major in Molecular Genetics) at Ferrara University (Italy) and graduated cum laude in 1996. In 2001 she obtained a PhD from Ferrara University on a thesis entitled “Molecular bases of APC resistance and factor V deficiency in thrombophilia” under the supervision of Prof. Francesco Bernardi. Thanks to an EMBO Long-Term Fellowship she then moved to Maastricht (The Netherlands) for post-doctoral training in coagulation biochemistry and thrombin generation in Prof. Jan Rosing’s laboratory. In 2006 she was awarded a VIDI grant from the Netherlands Organisation for Scientific Research for a project on inherited thrombophilia, which allowed her to establish her own research group. Currently she is an Associate Professor of Biochemistry at Maastricht University.
Her research interests focus on the genetics and functional characterisation of coagulation defects that predispose to bleeding or thrombotic disorders. Her main areas of expertise are factor V, the protein C pathway and the modulation of thrombin activity by fibrinogen γ’. From 2011 to 2014 she also served as a co-chairman of the SSC Subcommittee on Plasma Coagulation Inhibitors of the ISTH.